Products > Resins for Peptide Synthesis > Sulfonyl Hydrazide Resin
Sulfonyl Hydrazide Resin
Catalog # |
Cross Linker (DVB) |
Particle Size
(mesh) |
Loading
(-N:mmol/g resin)
|
Price (US $) |
25 g |
100 g |
500g |
151909
151910 |
1%
1% |
100-200
200-400 |
1.0-3.0
1.0-3.0 |
298.00
298.00 |
698.00
698.00 |
2,385.00
2,385.00 |
|
The sulfonyl hydrazide resin was generally used as a scavenger to remove the ketone [1]. In a “catch-release” strategy, the ketone solution was directly transferred to a reaction vessel containing Ps-TsNHNH2 resin via cannula. After thionyl chloride cleavage and purification, a series of 1,2,3 – thiadiazdes were prepared with various substituents at 5 position [2].
References
[1] O. Atici, React. & Func. Polym., 1997, 34, 175
[2] Y. H. Hu, et al., J. Org. Chem., 1999, 64, 1049
|