Products > Resins for Peptide Synthesis > 4-Methoxytrityl Chloride Resin





4-Methoxytrityl Chloride Resin

Catalog #

Cross Linker (DVB)

Particle Size
(mesh)

Loading
(mmol/g)

Price (US $)

10 g

25 g

100 g

500g

151321
151322
151323
151324

1%
1%
1%
1%

100-200
100-200
200-400
200-400

0.4-1.0
1.0-1.6
0.4-1.0
1.0-1.6

138.00
141.00
138.00
141.00

220.00
231.00
220.00
231.00

502.00
533.00
502.00
533.00

1,950.00
2,095.00
1,950.00
2,095.00


The 4-methoxytrityl chloride resin, which is slightly more acid-labile than Methyltrityl Resin, is used for the solid phase immobilization of carboxylic acids, alcohols, thiols and amines [1-4]. Cleavage is generally achieved using 1-5% TFA in DCM containing 5% TIS.

References

[1] K. Barlos, et al., Tetrahedron Lett., 1989, 30, 3943.
[2] S. Eleftheriou, et al., Tetrahedron Lett., 1999, 40, 2825.
[3] S. Mourtas, et al., Tetrahedron Lett., 2001, 42, 2201
[4] S. Mourtas, et al., Tetrahedron Lett., 2003, 44, 179